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Tax Senior Analyst

Vertex Pharmaceuticals Incorporated
paid time off, 401(k)
United States, Massachusetts, Boston
50 Northern Avenue (Show on map)
Feb 03, 2026

Job Description

General Summary:

Reporting to the Director of Global Tax Reporting and N.A. Compliance, this role will assist the tax team members with the preparation/review of the overall accounting for income taxes under U.S. GAAP, federal and state income tax filing calculations, the tax technology roadmap, and various tax planning/project initiatives. The successful candidate must be well organized and able to multi-task in a fast-paced environment with the ability to build relationships with cross-functional teams. This role will work with both internal and external tax professionals as well as individuals across all departments in the company.

Key Duties and Responsibilities:

  • Prepares accounting for income tax computations and confirms adherence to internal controls under Sarbanes-Oxley.
  • Prepares monthly and quarterly account analyses and reconciliations for tax-related accounts.
  • Prepares calculations and compiles support for N.A. tax compliance, as directed.
  • Prepares write-ups in response to N.A. tax controversy/notices as directed.
  • Performs input into standardized processes, including the use of OneSource Tax Provision software for computation of U.S. GAAP income tax accounting.
  • Performs responsibilities with an emphasis on technology and data, and identifying potential opportunities for process improvement and automation.
  • Participate in research tax credit studies in partnership with outside providers.
  • Partner with tax and cross-functional team members on ad-hoc projects.

Knowledge and Skills:

  • Word, PowerPoint, advanced knowledge of Excel
  • OneSource Tax Provision and OneSource Income Tax
  • Strong written, verbal, and organizational skills
  • Oracle, Hyperion, Alteryx, SAP, Snowflake, and PowerBI are a strong plus but not required
  • Prior corporate Accounting/Tax office experience is a strong plus but not required

Education and Experience:

  • Bachelor's Degree in Accounting or equivalent
  • Typically requires 3-5 years of experience in Big Four/corporate in-house tax department or the equivalent combination of education and experience

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Pay Range:

$0 - $0

Disclosure Statement:

The range provided is based on what we believe is a reasonable estimate for the base salary pay range for this job at the time of posting. This role is eligible for an annual bonus and annual equity awards. Some roles may also be eligible for overtime pay, in accordance with federal and state requirements. Actual base salary pay will be based on a number of factors, including skills, competencies, experience, and other job-related factors permitted by law.

At Vertex, our Total Rewards offerings also include inclusive market-leading benefits to meet our employees wherever they are in their career, financial, family and wellbeing journey while providing flexibility and resources to support their growth and aspirations. From medical, dental and vision benefits to generous paid time off (including a week-long company shutdown in the Summer and the Winter), educational assistance programs including student loan repayment, a generous commuting subsidy, matching charitable donations, 401(k) and so much more.

Flex Designation:

Hybrid-Eligible Or On-Site Eligible

Flex Eligibility Status:

In this Hybrid-Eligible role, you can choose to be designated as:
1. Hybrid: work remotely up to two days per week; or select
2. On-Site: work five days per week on-site with ad hoc flexibility.

Note: The Flex status for this position is subject to Vertex's Policy on Flex @ Vertex Program and may be changed at any time.

#LI-Hybrid

Company Information

Vertex is a global biotechnology company that invests in scientific innovation.

Vertex is committed to equal employment opportunity and non-discrimination for all employees and qualified applicants without regard to a person's race, color, sex, gender identity or expression, age, religion, national origin, ancestry, ethnicity, disability, veteran status, genetic information, sexual orientation, marital status, or any characteristic protected under applicable law. Vertex is an E-Verify Employer in the United States. Vertex will make reasonable accommodations for qualified individuals with known disabilities, in accordance with applicable law.

Any applicant requiring an accommodation in connection with the hiring process and/or to perform the essential functions of the position for which the applicant has applied should make a request to the recruiter or hiring manager, or contact Talent Acquisition at ApplicationAssistance@vrtx.com

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