Research Technician II - BERNT LAB

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A Brief Overview
This entry-level research technical role participates in a planned research projects by performing research protocols, experimental procedures and other laboratory tasks under direct supervision. May occasionally exercise minimal discretion and judgment in execution and interpretation of experiments, and of data derived.

This position is a part of an exciting research program at the Children's Hospital of Philadelphia (CHOP) to study mechanisms and develop targeted therapy approaches for patients with leukemia. The project uses patient samples, cell lines and model systems to discover new therapies for this devastating disease. For more detailed information on this research program, please visit: https://www.theberntlab-chop.org/

We are looking for a bright, meticulous, motivated and curious individual who would like to learn about childhood leukemias and master an array of advanced biomedical techniques during a 1+ year work with our group. Responsibilities include:

• Preparation of primary patient samples for proteomic, transcriptomic and epigenomic analysis including single cell analysis
• Data entry and analysis, data base maintenance
• Management of murine colony for translational studies using syngeneic and patient derived xenograft models
• Assistance in follow up studies in leukemia cell lines and selected samples using standard molecular biology techniques (PCR, flow cytometry, basic molecular biology).
• Assistance in maintaining the lab (orders and shipping, maintenance of leukemia cell lines, maintenance of reagents, maintenance of lab meeting schedule)

Candidate:

We are hoping to hire a highly reliable, responsible and motivated individual who is interested in a career in medicine or biomedical research, and ready to take on a crucial part in our program. Prior research experience in standard molecular biology techniques or bioinformatics are highly desirable. Organizational skills, the ability to work independently, and highest attention to details are a must.

Benefits:

• Potential for hands on experience in cutting edge leukemia research including novel therapeutic targets and "-omics" approaches (genomics, epigenomics, proteomics)
• Training in specific biocomputational approaches (proteomic, transcriptomic pipelines) can be provided for candidates with prior experience in bioinformatics and an interest in pursuing additional training
• Possibility to shadow clinics and inpatient wards in Pediatric Oncology
• In depth exposure to different career paths - Physicians, Physician-Scientists, PhD-scientists, Bioinformaticians - which will greatly help in making future career choices
• Recommendations from leading institution in the field for future applications in graduate programs (MD, MD/PhD, PhD)
• Competitive salary, benefits
• Fun, dynamic group

What you will do

• Performs routine tests / experiments under the direction of principal investigator, supervisor or other designee
• Performs research procedures on experimental samples as directed
• Records and checks experiments/ results for completeness and accuracy
• Performs calculations and maintains appropriate log and lab notebooks
• Performs tasks that require familiarity with fundamental techniques and lab equipment
• May assist with planning specific research protocols and procedures
• Maintains office, lab area, solutions, reagents, supplies and equipment, disposes of specimens, media and other materials (using appropriate procedures)
• Assists in care and maintenance of lab equipment
• May coordinate schedules of tests and procedures
• Attends courses, seminars, and lab meetings to expand knowledge of research and laboratory techniques
• Records results, organizes data and maintains lab notebook in an organized manner
• Compiles and helps analyze data, prepares charts, graphs, and results of studies as directed
• Conducts literary searches as directed

Education Qualifications

• High School Diploma / GED Required
• Associate's Degree Preferred
• Bachelor's Degree Preferred

Experience Qualifications

• At least one (1) year of related classroom experience or successful completion of a technical training program (eg. Wistar, WPSI) and research laboratory experience Required
• At least two (2) years of related classroom experience or successful completion of a technical training program (eg. Wistar, WPSI) and research laboratory experience Preferred

Skills and Abilities

• Intermediate understanding of lab procedures, protocols, and equipment.
• Basic exposure to lab specific experiments / techniques and scientific analysis
• Excellent verbal and written communications skills
• Excellent organizational skills
• Solid critical thinking / problem-solving skills
• Solid analytical skills

To carry out its mission, CHOP is committed to supporting the health of our patients, families, workforce, and global community. As a condition of employment, CHOP employees who work in patient care buildings or who have patient facing responsibilities must receive an annual influenza vaccine. Learn more.

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SALARY RANGE:

Salary ranges are shown for full-time jobs. If you're working part-time, your pay will be adjusted accordingly.

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At CHOP, we are committed to fair and transparent pay practices. Factors such as skills and experience could result in an offer above the salary range noted in this job posting. Click here for more information regarding CHOP's Compensation and Benefits.