Principal Tissue Engineer

Overview:

Draper is an independent, nonprofit research and development company headquartered in Cambridge, MA. The 2,000+ employees of Draper tackle important national challenges with a promise of delivering successful and usable solutions. From military defense and space exploration to biomedical engineering, lives often depend on the solutions we provide. Our multidisciplinary teams of engineers and scientists work in a collaborative environment that inspires the cross-fertilization of ideas necessary for true innovation. For more information about Draper, visit www.draper.com.

Job Description Summary:

Job Description:

Duties/Responsibilities
* Independently drive solutions to complex problems.
* Develop requirements for innovative bioengineering solutions, propose ways forward when customer requirements are unclear or incomplete, and adapt appropriately to changes in requirements.
* Subject Matter Expert (SME) able to perform advanced research and analysis for complex bioengineering solutions.
* Develop, document, and teach best practices to less experienced bioengineers; Demonstrate strong organization, planning, and time management skills to achieve goals.
* Performs other duties as assigned.

Skills/Abilities
* Strong foundation in biology and/or engineering principles.
* Team player, dedicated, collaborative, observant, and motivated.
* Excellent organizational skills, attention to detail, and verbal and written communication skills.
* Creative problem-solving skills and a passion for innovation.
* Excellent time management skills with the proven ability to meet deadlines and prioritize tasks.
* Enthusiasm for learning and participating in mentorship/mentoring.
* Proficiency with Microsoft Office Applications.

Education
Requires either a Bachelor's Degree in Bioengineering, Biomedical Engineering, Biochemistry, Chemistry, Cell Biology, Immunology, Microbiology, Molecular Biology, Mechanical Engineering, Chemical Engineering, Physics or related fields. Master's degree preferred.

Experience
Requires 5-7 years of Bioengineering or related engineering experience.

Additional Job Description:

Additional duties/responsibilities:

• Serve as an cell biologist and/or tissue engineer subject matter expert for interdisciplinary teams including biologists, engineers, chemists, bioinformaticians, etc.
• Lead and support technical research projects, including developing the research approach and coordinating deliverables, timelines and budgets, in alignment with Draper business and technical strategies
• Support business development efforts through ideation, proposal writing, and customer outreach
• Coordinate, perform or support experiments in Draper's biosafety level 2 (BSL-2) and 3 (BSL-3) laboratories with Draper's advanced in vitro platform technologies (microphysiological system or organs-on-chip)
• Apply cell biology and tissue engineering fundamentals to develop cell and tissue models and assays within Draper's in vitro tissue culture systems under different contexts of use; work collaboratively with a team and troubleshoot as needed
• Collect, analyze, organize, and effectively present data to internal management, external customers and sponsors, and for publication
• Complete all necessary training, adhere to all laboratory, institutional, and government regulations, and contribute to an environment of safety and compliance

Preferred qualifications:

• PhD in biology or engineering discipline and several (6+) years of postdoctoral and/or industry experience in a laboratory/R&D setting
• Expertise writing innovative R&D proposals for government sponsors (contacts, grants) or commercial sponsors and generating intellectual property
• Expertise developing tissue engineering models, specifically pulmonary, cardiac, liver, gastrointestinal, neural and/or lymphoid tissues, under different contexts of use
• Expertise in primary mammalian cell and tissue culture, including complex multi-cell type co-cultures, organoid cultures, stem cell or iPSC cultures, and isolating, differentiating and phenotypically and functionally characterizing mammalian cells.
• Expertise applying fundamental biology knowledge to advanced and novel in vitro cell and tissue culture systems, including microfluidic devices, microphysiological systems (MPS), and/or organ-on-chip (OoC) technologies
• Expertise with a variety of cell and molecular biology assays and technologies, such as viability assays, immunofluorescence staining, confocal imaging, ELISA/Luminex, flow cytometry, FACS, DNA or RNA extraction, qPCR, and multi-omics (e.g. transcriptomics, proteomics, metabolomics)
• Microbiology experience, including experience working with bacterial or viral pathogens or with biological toxins within mammalian cell-based systems; experience studying host-pathogen interactions; experience studying or modeling microbiomes.
• Some experience with immunology, image processing, synthetic biology, genetic engineering, bioinformatics and data analytics, biostatistical analyses, in silico modeling and/or laboratory automation.

Security Requirement:Applicants selected for this position will be required to obtain and maintain a government security clearance.

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Our work is very important to us, but so is our life outside of work. Draper supports many programs to improve work-life balance including workplace flexibility, employee clubs ranging from photography to yoga, health and finance workshops, off site social events and discounts to local museums and cultural activities. If this specific job opportunity and the chance to work at a nationally renowned R&D innovation company appeals to you, apply now www.draper.com/careers.

Draper is committed to creating an inclusive environment. We understand the value of inclusivity and its impact on a high-performance culture. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, disability, age, sexual orientation, national origin, veteran status, or genetic information. Draper is committed to providing access, equal opportunity, and reasonable accommodation for individuals with disabilities in employment, its services, programs, and activities. To request reasonable accommodation, please contact hr@draper.com.