Research Lab Manager 1 - Kranic's Lab

Department: MED-Neurology
Salary/Grade: EXS/6

Target hiring range for this position will be between $56,782-$79,850 per year. Offered salary will be determined by the applicant's education, experience, knowledge, skills and abilities, as well as internal equity and alignment with market data.

Job Summary

Manages daily operations of a research lab. Monitors lab performance, analyzes and reviews results, and supervises development and implementation of new protocols. Assigns work and supervises lab personnel and reviews technical operations ensuring that all processes, protocols and procedures are quality controlled and functioning up to standards. Develops implements and administers budgets, grant and administrative procedures. Co-authors scientific papers for presentation and publication and coordinates writing, submission and administration of grants. This position will manage the lab of Dr. Dimitri Krainc. More information regarding the lab can be found here: https://labs.feinberg.northwestern.edu/krainc/index.html

Specific Responsibilities:

• Manages technical operations of a lab involved in scientific research activities.
• In consultation with Principle Investigator (PI) organizes and plans experiments ensuring those project objectives are attained.
• Oversees and guides lab staff in review of results and recommendation of changes to protocols to improve validity and accuracy.
• Conducts more complex experiments and analysis.
• Using an advanced level of skill, completes the following activities

Molecular Biology:

• DNA, RNA, Protein isolation, purification and expression
• Southern, Northern, Western blotting
• PCR, RT-PCR
• Plasmid preparation
• Cloning, mapping and sequencing of DNA
• Recombinant virus production and purification

Cellular Biology:

• Cell culture, cell isolation
• Functional studies
• Transfection

Histology:

• Tissue fixation/processing: embedding, preparation of blocks and sectioning, staining
• Immunohistochemistry
• Microscopy

Immunology:

• Flow cytometry
• ELISA, Elispot assay
• Cytokine assay
• Antibody production and purification

Animal:

• Husbandry
• Breeding and screening transgenic mice
• Dissections
• Blood collection
• Surgical procedures
• Database management of colony

Administration

• Oversees and manages collection, maintenance, analysis and evaluation of data that will be used in grant submissions, presentations and publications.
• Ensures that information is entered correctly into databases.
• Assists PI in reviewing, analyzing, interpreting, summarizing, formatting, editing, and preparing tables, charts, graphs, progress and final reports, etc.
• Coordinates between sponsoring agencies, collaboration organizations and/or other research and/or educational institutions.
• Ensures research regulations are adhered to, IRB and ACUC approvals in place, material transfer agreements properly executed, and that radiation and lab safety requirements are up to date and implemented.

Finance

• Manages lab budget and inventory including purchasing of supplies and services ensuring that they are necessary, reasonable and project related.
• Orders and maintains inventory of lab supplies, chemicals, equipment and instrumentation and may distribute intra-departmental charges.
• Negotiates with vendors, obtain quotes and arrange for demos of large equipment.

Supervision

• Trains, directs, assigns duties to & supervises lab EEs, students, residents &/or fellows.
• Provides instruction to lab users on technically complex procedures, equipment & instruments.
• Typically manages a lab budget of $1,000,000-$3,000,000; 1,000 - 3,000 nasf of space & supervises 5-15 lab members.

Miscellaneous

• Other duties as assigned.

Minimum Qualifications: (Education, experience, and any other certifications or clearances)

• Successful completion of a full 4-year course of study in an accredited college or university leading to a bachelor's or higher degree in a scientific major or related; OR appropriate combination of education and experience and 6 years' lab/bench or other relevant experience required; OR
• Successful completion of a full course of study in an accredited college or university leading to a master's or higher degree in a scientific major or related; OR appropriate combination of education and experience and 4 years' lab/bench or other relevant experience.
• Supervisory or project management experience required.

Benefits:
At Northwestern, we are proud to provide meaningful, competitive, high-quality health care plans, retirement benefits, tuition discounts and more! Visit us at https://www.northwestern.edu/hr/benefits/index.html to learn more.

Work-Life and Wellness:
Northwestern offers comprehensive programs and services to help you and your family navigate life's challenges and opportunities and adopt and maintain healthy lifestyles.
We support flexible work arrangements where possible and programs to help you locate and pay for quality, affordable childcare and senior/adult care. Visit us at https://www.northwestern.edu/hr/benefits/work-life/index.html to learn more.

Professional Growth & Development:
Northwestern supports employee career development in all circumstances whether your workspace is on campus or at home. If you're interested in developing your professional potential or continuing your formal education, we offer a variety of tools and resources. Visit us at https://www.northwestern.edu/hr/learning/index.html to learn more.

Northwestern strongly recommends COVID-19 vaccinations and boosters for people who can obtain them as a critical tool for minimizing severe illness. More information can be found on the COVID-19 and Campus Updates webpage.

The Northwestern campus sits on the traditional homelands of the people of the Council of Three Fires, the Ojibwe, Potawatomi, and Odawa as well as the Menominee, Miami and Ho-Chunk nations. We acknowledge and honor the original people of the land upon which Northwestern University stands, and the Native people who remain on this land today.

Northwestern University is an Equal Opportunity, Affirmative Action Employer of all protected classes, including veterans and individuals with disabilities. Women, racial and ethnic minorities, individuals with disabilities, and veterans are encouraged to apply. Click for information on EEO is the Law.

#LI-GY2